Enjoy the taste of creamy and rich Italian Alfredo in this delicious Americanized Chicken Alfredo Casserole! It’s tasty and savory, and serves six. This savory and cheesy casserole is a droolworthy family favorite in my home and for valid reasons! My husband, toddler, and myself all adore this dish because of it’s cheesy biscuit-y goodness. The hidden biscuits appear as a wonderful, tasty surprise in each bite—along with the cheese, chicken, and broccoli! If you like chicken casseroles, then you’ll love my Sour Cream Chicken Enchilada Casserole, KFC Famous Bowl Casserole, and my Chicken Fajita Casserole recipes!
Broccoli is a cruciferous vegetable that resembles a mini tree and belongs to the plant species known as Brassica oleracea. Healthline’s article reports that broccoli is a nutritional powerhouse filled with vitamins, minerals, and antioxidants.
My family friendly casserole recipe contains fresh broccoli florets, chicken breast, Alfredo sauce, milk, Italian seasoning, garlic powder, salt, pepper, biscuit dough (such as Pillsbury refrigerated biscuit dough), and grated cheddar cheese, and is done in about 50 minutes.
How to make the best Chicken Alfredo Casserole
STEP 1: Preheat your oven and coat a 9×13 inch baking dish with cooking spray.
STEP 2: Steam the broccoli or cover it and place in the microwave.
STEP 3: In a large bowl, combine the broccoli, chicken, Alfredo sauce, milk, Italian seasoning, garlic powder, salt, and pepper. Add the biscuit pieces and mix.
STEP 4: Bake for about a half an hour and remove from oven. Evenly spread the grated cheese over the top and bake in the oven for 15-20 minutes, until the casserole has cooked through.
Tips and Substitutions
Cooking the chicken. An easy way to cook the chicken is to do one of two things: 1) Place the washed chicken in a crockpot and let it cook while you work on any setting. When it’s done, remove the chicken and place in a bowl where you can shred it with two forks, or 2) Bake on a foil-lined and sprayed baking sheet at 450° F for 20-25 minutes, until there is no pink in the center.
Broccoli. You can use frozen broccoli. If you do, use two 16 oz. frozen bags, thawing them before adding them to the mixture. If you do not thaw them, then add 10-15 minutes to the cook time. Frozen vegetables are a great idea and are a huge timesaver if you’re in a hurry and don’t have time to chop fresh broccoli.
Health Benefits of Broccoli
Raw or cooked, broccoli is an excellent source of vitamin C. Just one-half cup of cooked broccoli provides 84 percent of the reference daily intake (RDI) –more than one-half orange can offer in terms of vitamin C.
The high antioxidant content of broccoli may be its highest contributing factor to human health. Antioxidants neutralize damage caused by free radicals. Free radicals occur from living everyday modern life. Eating foods high in antioxidants can actually reduce blood sugar, cholesterol levels, oxidative stress, and slow down or prevent chronic disease development.
Additionally, Healthline’s article states that broccoli contains high amounts of the antioxidants lutein and zeaxanthin, which may prevent oxidative stress and cellular damage in the eyes. In summary, broccoli contains multiple potent antioxidants that may support healthy cells and tissues in the human body.
More recipes you’ll want to make!
Slow Cooker White Chicken Chili
Southern Style Oven “Fried” Chicken with Mashed Potatoes and Corn
Final Thoughts
Finally, if you make this Chicken Alfredo Casserole, be sure to leave a comment and/or give this recipe a rating! I love to hear from everyone who makes this recipe and always try my best to respond to all comments.
If you do make this recipe, don’t forget to tag #elisemccollister on Instagram! It makes me so happy to see your recipe photos!
Chicken Alfredo Casserole
Ingredients
- 3 c broccoli florets fresh, chopped
- 1 lb. chicken breast cooked and chopped into pieces
- 15 oz. jar Alfredo sauce
- 2 tbsp milk
- 1 tsp Italian seasoning
- 1/2 tsp garlic powder
- 1/2 tsp salt
- 1 tsp pepper
- 1 (7.5 oz.) refrigerated can biscuit dough such as Pillsbury, cut into sixths
- 2 c cheddar cheese freshly grated
Instructions
- Preheat oven to 350° F. Coat a 9×13-inch baking dish with cooking spray.
- Steam the broccoli or cover it with a wet paper towel and place in the microwave for two minutes.
- In a large bowl, combine the broccoli, chicken, Alfredo sauce, milk, Italian seasoning, garlic powder, salt, and pepper. Add the biscuit pieces and mix well.
- Bake for 25-30 minutes and remove from oven. Evenly spread the grated cheese over the top and bake in the oven for another 15-20 minutes, until the casserole has cooked through and the biscuits have bubbled up.
Nutrition (per serving)
Share this recipe!
Elise’s Kitchen Favorites
Thanks – I will put this dish on our meal plan for next week. However, what is Alfredo sauce, can I substitute it with something else ? I don’t think we have that here 🙁
Hi Line!
I believe it’s called “fløde og ost” in Denmark. You buy some parmesan cheese, some cream and perhaps some butter, garlic and parsley and then whisk it all together in a bowl and add it to your pasta. Here is my Alfredo sauce from my fettucine Alfredo recipe:
Ingredients:
• 4 tablespoons butter
• 1 ½ cup heavy cream
• 1 cup freshly shredded parmesan
• Salt
• Pepper
• Parsley for garnish, chopped
Directions:
1). Melt the butter in a medium skillet at low-medium heat. Add the heavy cream, stirring constantly. Let the mixture bubble and thicken for 2-3 minutes.
3). Add the parmesan, continuing to stir to thicken the sauce, for 5-7 minutes. Add salt and pepper to taste.
4). Remove from heat and mix in with the Chicken Alfredo Casserole recipe (this will be your Alfredo sauce).
I read online that the “closest to Alfredo sauce in Denmark would be Mornay sauce which you can buy at most places.”
Hope you love this recipe as much as we do!
Hugs! <3 ~Elise